Senior Director Clinical Research Scientist

Overview Incyte is a biopharmaceutical company focused on the discovery, development, and commercialization of novel medicines to meet serious unmet medical needs in oncology and inflammation and autoimmunity. Incyte is committed to the rigorous pursuit of research and development excellence to improve the lives of patients, make a difference in health care, and build sustainable value. The Company strives to discover and develop first-in-class and best-in-class medicines-advancing a diverse portfolio of large and small molecules.

Position Overview We are seeking a Clinical Scientist to join our Early Clinical Development Group at a level commensurate with experience (Associate Director through Executive Director).

This role is intentionally designed to attract both emerging leaders and experienced strategic contributors. Depending on level, you will contribute to or lead early clinical development and clinical pharmacology programs, with increasing ownership, strategic influence, and cross-functional leadership at more senior levels. You will have the opportunity to work across the full product lifecycle—from First-in-Human studies through approval and post-marketing—within a collaborative, science-driven environment that values curiosity, innovation, and continuous learning.

Key Responsibilities: Core Responsibilities (All Levels)

Contribute to the design, execution, and interpretation of early clinical and clinical pharmacology studies Collaborate cross-functionally with Clinical Operations, Translational Sciences, Quantitative Clinical Pharmacology, and Statistics Support development of clinical documents including protocols, study reports, and regulatory submissions Analyze and interpret clinical safety and efficacy data in collaboration with Medical and Scientific teams Maintain awareness of competitive landscape and emerging standards of care Ensure adherence to timelines, budgets, SOPs, and regulatory requirements Present data internally and contribute to external scientific communications

Additional Responsibilities by Level Associate Director

Lead components of clinical studies and contribute to program-level strategy Draft and independently own sections of key clinical and regulatory documents Collaborate closely with cross-functional partners to execute study deliverables Present findings to internal teams

Director / Senior Director

Lead clinical studies and drive cross-functional execution Contribute meaningfully to clinical development strategy Serve as a scientific leader on project teams and influence decision-making Mentor junior team members and contribute to team development

Executive Director

Provide strategic leadership across programs or therapeutic areas Shape and drive clinical development strategy and represent programs to governance bodies Influence portfolio-level decisions and external collaborations Serve as a recognized subject matter expert internally and externally Lead high-visibility initiatives, including regulatory interactions and scientific presentations

Qualifications Minimum Requirements

PhD, PharmD, or MD with 5+ years of relevant experience, OR BS/MS with 10+ years of relevant experience Experience in early clinical development, clinical pharmacology, or a related discipline Strong analytical, communication, and problem-solving skills Ability to work independently and collaboratively in a dynamic environment

Additional Experience by Level Associate Director

Experience contributing to clinical studies and cross-functional teams Demonstrated ability to analyze and interpret clinical data

Director / Senior Director

Proven experience leading clinical studies or key program components Ability to influence cross-functional teams and contribute to strategy

Executive Director

Extensive experience leading clinical development programs Strong track record of strategic leadership and influencing senior stakeholders