Payroll Manager

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Rhythm is a global, commercial-stage biopharmaceutical company committed to transforming the lives of patients and their families living with rare neuroendocrine diseases. We develop medicines for previously untreatable or undertreated diseases and provide meaningful support for healthcare providers and patients and their families. We recognize the courage it takes for patients and their caregivers to begin their journey of advocacy to find the answers they need. Their courage inspires us to challenge convention, ask bold questions and seek answers for them. Every day, we strive for excellence through our willingness to adapt, learn, and our tenacity to overcome barriers, together.

We offer a fast-paced and collaborative work environment, with a competitive compensation and benefits package, including equity grants and the opportunity to participate in our employee stock purchase plan. We foster an environment that is supportive and fun – enabling us to bring our best each day toward achieving our goals. Working together, we'll succeed.

We are centrally located in Boston's Back Bay neighborhood, easily accessible by several modes of public transportation and walking distance to much of what the city has to offer.

We continue to grow, so if you don't see anything here that currently fits your qualifications, please visit again to see what roles we have open.

Thank you for considering Rhythm.

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Note to agencies: Rhythm values our partnerships with recruiting firms and will only work with those who have an established relationship and signed contract. Authorization to work on a role and/or submit resumes will come from HR only, so please do not forward any agency resumes. The company will not be responsible for any fees related to resumes that are unsolicited.

Payroll Manager

Boston, MA

Full Time

Accounting and Finance

Mid Level

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Company Overview Rhythm is a global, commercial-stage biopharmaceutical company committed to transforming the lives of patients living with rare neuroendocrine diseases. We develop medicines for previously untreatable or undertreated diseases. We recognize the courage it takes for patients and their caregivers to begin their journey of advocacy to find the answers they need. Their courage inspires us to challenge convention, ask bold questions and seek answers for them. Every day, we strive for excellence through our willingness to adapt, learn, and our tenacity to overcome barriers, together.

Overview Rhythm Pharmaceuticals is seeking a hands-on, detail-oriented Payroll Manager to join our Finance team. In this role, you will be directly involved in overseeing and processing North America's domestic payroll operations. The ideal candidate will have experience with ADP Workforce Now and a strong understanding of payroll compliance with federal, state, and local tax laws and regulations. This position is based in Boston and follows a hybrid work model to promote collaboration and flexibility. Responsibilities and Duties Manage and process U.S. multi-state regular bi-weekly payrolls for 270+ employees, using ADP Workforce Now. Manage and process Canada's regular (semi-monthly) payroll. Process off-cycle equity payrolls (RSU, NQ), bonuses , and terminations . Ensure payroll compliance with federal, state, and local payroll laws and regulations. Register payroll tax accounts in new tax jurisdictions and maintain validation tables in ADP. Partner with payroll providers to support payroll configuration updates. Stay current on ADP payroll system updates and training to maximize the return of investment from the payroll system. Manage US quarterly and year-end processes.