Senior Manager, Compliance Operations & Analytics

MISSION

Mirum Pharmaceuticals is a biopharmaceutical company dedicated to transforming the treatment of rare diseases. We are passionate about advancing scientific discoveries to become important medicines for rare disease patients. We are collaborative, creative, and experienced professionals and we’re looking to augment our team with other individuals who embody our values: care, be real, get it done, and have fun, seriously.

The Senior Manager, Compliance Operations & Analytics is responsible for supporting the strategic development, implementation, and ongoing enhancement of Mirum’s global healthcare compliance program. This role partners cross-functionally across Commercial, Medical Affairs, Market Access, Legal, Finance, Privacy, and IT to help ensure the Company meets its ethical and legal obligations to patients, healthcare professionals, employees, investors, and other stakeholders.

This position will lead operational aspects of the compliance program with a strong focus on compliance analytics, open payments and transparency reporting, auditing, and technology-enabled process improvement. The role will be responsible for overseeing federal and state transparency reporting operations, advancing data analytics and monitoring capabilities, and leveraging AI-enabled tools and automation to improve compliance efficiency, insights, and scalability in a growing biotech environment.

The ideal candidate is a proactive and business-oriented compliance professional with demonstrated experience building scalable compliance operations and analytic tools within a small to mid-size biotechnology or pharmaceutical company.

JOB FUNCTIONS/RESPONSIBILITIES

Compliance Operations and Program Management

• Support the ongoing development, implementation, and continuous improvement of Mirum’s comprehensive healthcare compliance program.

• Assist in the design, enhancement, and operationalization of compliance policies, SOPs, standards, and controls aligned with applicable federal and state healthcare laws, regulations, and industry guidance.

• Partner with Commercial, Medical Affairs, Market Access, Patient Services, and other business functions to provide practical, risk-based compliance guidance.

• Champion a culture of integrity and accountability in which employees view compliance as aligned with Mirum’s core values and business objectives.

• Support compliance committee activities, risk assessments, and remediation tracking.

• Assist with management of third-party compliance due diligence and monitoring activities.

Transparency Reporting Ownership

• Lead operational execution and ongoing enhancement of Federal Open Payments (Sunshine Act) and applicable state transparency reporting processes.

• Serve as the primary business owner for transparency reporting operations, including data governance, reconciliation, issue resolution, aggregate spend validation, and cross-functional coordination.

• Partner with Finance, Commercial Operations, Medical Affairs, and vendors to ensure accurate and timely data collection and reporting.

• Oversee pre-submission review, dispute resolution support, and post-submission reconciliation activities.

• Monitor evolving transparency reporting regulations and assess and update business process impacts as needed.

• Drive process improvements and automation initiatives to strengthen reporting accuracy, efficiency, and audit readiness.

Compliance Analytics & Monitoring

• Design, develop, and execute risk-based compliance monitoring and analytics programs using internal and external data sources.

• Conduct compliance audit activities to identify opportunities