MariTide, OSA and PIE Program Execution Lead

Career Category Project Management Job Description Join Amgen’s Mission of Serving Patients At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do. Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives. Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career. MariTide, OSA and PIE Program Execution Lead What you will do Let’s do this. Let’s change the world. In this vital role under the direction of the Chronic Weight Management Global Indication Lead, this role responsible for shaping and driving enterprise integrated execution across MariTide lifecycle expansion initiatives, including Obstructive Sleep Apnea (OSA), Patient Impact Expansion (PIE), and future obesity franchise opportunities. The role serves as the integrator across obesity Obstructive Sleep Apnea (OSA) and Patient Impact Expansion (PIE), being accountable for enabling cross-functional decision-making, influencing portfolio prioritization, and driving successful delivery of key milestones that maximize patient and business impact.

Lead enterprise portfolio integration and strategic influence across the cross-functional execution of the OSA indication and PIE initiatives, ensuring alignment across development, medical, regulatory, commercial, and operations functions.  Shape and operationalize the integrated program plan and critical timelines, driving accountability, visibility, and delivery against key milestones. Drive execution excellence across Global Development, Medical, Commercial, Regulatory, Market Access, and Operations functions to ensure successful execution of interconnected portfolio initiatives, proactively identifying risks, dependencies, and trade-offs to enable timely, decision-ready outcomes. Translate strategy into actionable plans, ensuring clear linkage between global objectives and operational effectiveness to support launch readiness and lifecycle management. Lead cross-functional alignment and decision-making, serving as a central integrator to ensure clarity, speed, and coordinated execution and prioritization across stakeholders. Own integrated program processes, including development of recommendations, strategic options, and decision-enablement materials for senior leadership and governance forums, enabling efficient, data-driven decisions at key program milestones. Influence prioritization of activities and resources, aligning execution against highest-value opportunities and portfolio objectives. Embed continuous improvement and cross-program learning into execution to enhance team effectiveness, agility, and speed to patient. Partner with senior leadership to identify and mitigate enterprise risks, dependencies, and operational challenges impacting program delivery. Lead cross-functional planning processes and ensure linkage between global strategy, business priorities, and operational execution. Anticipate emerging portfolio risks, competitive developments, and strategic opportunities and provide recommendations to senior leadership regarding priorities and execution strategies. Drive