Mass Spectrometry Chemist

General Matter is enriching uranium in America.

Our goal is to design, build, and operate the world’s lowest-cost enrichment services in the United States.

Our mission is to restore America’s ability to produce nuclear fuel—fuel that will power AI, advanced manufacturing, critical industries, and the next generation of nuclear reactors.

Ultimately, our work will help power national ambitions and enable a high-energy society.

We were incubated by Founders Fund, like Anduril and Palantir before us, and are backed by top-tier investors. Our lean, world-class team of engineers and operators is applying a first-principles approach to solving the problem of nuclear fuel production.

We are a mission-driven company with a culture of urgency, accountability, and transparency.

Help us build a high-energy society by making the cleanest, safest form of baseload energy the most affordable.

As a Mass Spectrometry Chemist at General Matter, you will play a critical role in establishing and advancing our analytical measurement capabilities for uranium isotopic analysis. You'll work hands-on with cutting-edge mass spectrometry instrumentation — including isotope-ratio mass spectrometry and ICP-MS systems — to develop, validate, and execute methods that directly support our enrichment operations and product certification. This is a rare opportunity to build measurement systems from the ground up at a next-generation nuclear facility during rapid commercial scale-up, where your technical work immediately impacts our ability to produce low-cost nuclear fuel at scale. If you seek high impact and are excited by fast-paced, intense, Skunkworks-style projects in service of a mission of national importance, we encourage you to apply to join our Chemistry team.

• Develop, optimize, and validate analytical methods for uranium isotopic analysis using mass spectrometry (isotope-ratio MS, ICP-MS)

• Perform isotopic sampling, sample preparation, and measurement workflows to support enrichment process monitoring and product certification

• Operate, maintain, calibrate, and troubleshoot mass spectrometry instrumentation to ensure measurement accuracy, precision, and reliability

• Integrate measurement systems with sample-handling workflows and support automation and process improvements

• Collaborate closely with the Chemistry team and cross-functional partners (Operations, Product Certification, Engineering) to define analytical requirements and deliver results that drive decision-making

• Document methods, maintain rigorous QA/QC protocols, and support regulatory and compliance reporting as