Scientist I, Protein Biology

Work Schedule Standard (Mon-Fri) Environmental Conditions Adherence to all Good Manufacturing Practices (GMP) Safety Standards, Cold Room/Freezers -22degreesF/-6degrees C, Office, Some degree of PPE (Personal Protective Equipment) required (safety glasses, gowning, gloves, lab coat, ear plugs etc.) Job Description About the Company Thermo Fisher Scientific Inc. (NYSE: TMO) is the world leader in serving science, with annual revenue of approximately $44 billion. Our Mission is to enable our customers to make the world healthier, cleaner, and safer. Whether our customers are accelerating life sciences research, solving analytical challenges, growing efficiency in their laboratories, improving patient health through diagnostics, or developing and manufacturing life-changing therapies, we are here to support them. Our global team delivers an outstanding combination of innovative technologies, purchasing convenience, and pharmaceutical services through our industry-leading brands, including Thermo Scientific, Applied Biosystems, Invitrogen, Fisher Scientific, Unity Lab Services, Patheon, and PPD. the The Antibody Team is involved in engineering and development of antibodies, with a deep focus on reagent quality and specificity. The core activities of team include design, development, purification, conjugation, and testing of antibodies in a variety of immunoassay applications using groundbreaking tools and technologies. The goal of the program is recombinant antibody development and creation of product-specific information to promote research use. Key Responsibilities ·        Design and execute immunoassays to support antibody development and validation programs. ·        Meticulous experimental planning and execution to meet program goals. ·        Timely record-keeping of results into data sheets and laboratory notebooks. ·        Attention to detail and adherence to schedules. ·        Communicate results clearly—in team meetings, written reports, and data presentations. ·        Regular mining of literature and keeping oneself up to date with developments in the field of antibody development. ·        Troubleshoot technical challenges and propose practical solutions to keep projects moving. Qualifications & Experience Education Applicants should hold a degree in a relevant life sciences discipline (protein biology, molecular biology, biochemistry, immunology, biotechnology, or a related field) at one of the following levels: ·        PhD (graduated within the last year) ·        Master's degree with a minimum of 3 years of relevant research experience Technical Skills & Experience ·        Immunoassay Applications : Demonstrated experience in immunoassay development and application testing, including ELISA, Western Blotting, Flow Cytometry, Immunocytochemistry (ICC), Co-immunoprecipitation (co-IP), and Immunohistochemistry (IHC). Advanced expertise in microscopy, spatial biology platforms, and multiplexed IHC/IF/ISH, with experience developing and analyzing high-content tissue imaging assays for protein expression and cellular phenotyping is highly advantageous. ·        Bioinformatics, Programming & AI literacy : Proficiency in Python, R, bioinformatics/computational biology and statistical tools like Pymol, Chimera, BLAST, Alphafold, ggplot etc. Proficiency in deep learning models and/or knowledge of large language models (LLMs), prompt engineering, and experience in implementing these tools to biological questions is highly desirable. ·         Molecular Biology : Solid foundation in molecular biology techniques including nucleic acid extraction, PCR, cloning, sequence analysis, and vector design. ·        Cell Culture Techniques : Practical experience in standard mammalian or other specialized cell culture techniques supporting protein expression, antibody production, or related workflows. ·        Antibody Development