Staff Accountant

Beeline Medicines is a clinical‑stage biotechnology company focused on developing and delivering category-leading precision therapies to transform the lives of people living with autoimmune and inflammatory diseases. With a portfolio of potential best-in-class and first-in-disease therapeutic candidates that directly target key pathways governing dysregulated immunological and inflammatory responses, the Company is developing medicines that have the opportunity to provide durable, life-changing impact. Led by an established executive team and backed by world-class life science investors, each day Beeline Medicines is determined to bring the scientific rigor and operational excellence to get to what matters for patients – realizing a world where people with immune-mediated diseases can live life fully.

The Staff Accountant is a foundational member of Accounting team, responsible for supporting the day-to-day accounting operations, monthly close process, and financial reporting activities of a clinical-stage biotech. This role provides accurate and timely accounting support across general ledger maintenance, accounts payable, account reconciliations, and expense reporting — contributing to the integrity of the financial records that underpin the organization's reporting and compliance obligations. Operating in a lean finance environment, the Staff Accountant is expected to bring attention to detail, a strong work ethic, and a genuine desire to build foundational accounting skills in a fast-paced, high-growth life sciences setting. This is an excellent opportunity for an early-career accounting professional to gain broad exposure to all aspects of biotech accounting and develop their skills alongside an experienced Finance team.

Hybrid - This position follows a hybrid work schedule, requiring a minimum of two (2) days on-site per week — currently designated as Tuesday and Wednesday. Additional on-site days may be required based on business needs, team priorities, or leadership direction.

• Support the monthly financial close process — preparing and posting journal entries, performing account reconciliations, and assisting with the preparation of close workpapers across assigned accounting areas including prepaid expenses, accruals, and fixed assets.

• Process and manage accounts payable activities — reviewing and coding vendor invoices, coordinating approval workflows, maintaining vendor records, and supporting timely and accurate payment processing in accordance with company policies.

• Prepare and maintain accounting schedules and supporting documentation for assigned balance sheet accounts — ensuring all reconciliations are completed accurately, on schedule, and supported by appropriate backup documentation.

• Support clinical and research program accrual processes — working with Clinical Operations, Finance, and external vendors to track program expenditures, estimate accruals, and ensure accurate recording of CRO and research-related costs.

• Assist in the preparation of external audit support — organizing workpapers, preparing schedules, and gathering documentation in response to auditor requests under the direction of the Manager, Accounting.

• Support accounts payable vendor management — maintaining accurate vendor master data, processing new vendor setups, and ensuring W-9/W-8 compliance in coordination with Tax and Finance leadership.

• Contribute to the