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Associate Scientist, Host Cell Protein (HCP) Analytics

Regeneron

TARRYTOWNEntry
Sign in to applyVerified 2h ago
Location
TARRYTOWN
Work model
On-Site
Level
Entry
Posted
9h ago

About this role

At Regeneron, we use science and innovation to develop life-changing medicines for people with serious diseases. We are seeking a Associate Scientist to join our Product Biochemistry group, supporting our Host Cell Protein (HCP) analytical program. In this role, you will focus on polyclonal antibody purification, ELISA method development, and related reagent generation activities that underpin our HCP impurity monitoring strategy across biologics programs. This position offers the opportunity to play a key role in enabling high-quality analytical support for process development, CMC, and regulatory filings, contributing to a fast-growing, science-driven organization making a meaningful difference to patients worldwide. When & where: Shift Requirements: Full-time, standard business hours Location: On-site laboratory setting Flexibility & travel: Minimal to no travel; on-site presence required to support laboratory operations What you'll do: Purify polyclonal antibodies from rabbit/goat bleeds immunized with host cell protein antigens, using affinity chromatography and other standard purification workflows Optimize and streamline purification protocols to improve yield, purity, reproducibility, and throughput Support ELISA method development, qualification, and troubleshooting for HCP detection and quantitation Prepare, aliquot, and manage critical reagents (antibodies, conjugates, standards, buffers) to ensure consistent assay performance Document all experimental work in the electronic laboratory notebook (ELN) in accordance with defined procedures and departmental standards, and provide documentation upon request to support internal reviews, tech transfer, or regulatory submissions Collaborate cross-functionally with process development, QC, and analytical teams to align on reagent needs and assay performance criteria Contribute to continuous improvement of laboratory workflows and best practices The environment and physical rhythms of this role: This is a hands-on, on-site laboratory role centered on protein purification and immunoassay work, requiring rigorous attention to detail and consistent documentation practices. Flexibility to work independently, manage multiple tasks in parallel, and collaborate effectively within a team-oriented environment is required. Let's find out if we're a fit: Must-haves: BS/MS in Biochemistry, Chemistry, Molecular Biology, or a related life science discipline Hands-on experience with protein purification (affinity chromatography, e.g., Protein A/G, antigen-affinity columns; AKTA or equivalent FPLC systems preferred) Working knowledge of ELISA and general immunoassay techniques Ability to work independently, manage multiple tasks in parallel, and maintain rigorous attention to detail Excellent written and verbal communication skills; team-oriented mindset Preferred / nice-to-haves: Prior ELN experience Strong documentation habits Thrive today. Grow tomorrow. Student Loan Paydown program & Tuition Reimbursement Family Care Benefits Relocation Assistance Inclusion, Culture and Well-Being programs (including physical & mental health) Does this sound like you? Apply now to take your first step towards living the Regeneron Way! We are committed to building a workplace with an inclusive culture. Regeneron is an equal opportunity employer and all  qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, sexual orientation, gender identity or expression, gender reassignment, marital or civil partnership status, civil status, pregnancy or parental status, age, disability, nationality, citizenship status, ethnic or national origin, membership of the Traveler community, familial status, genetic information, military or veteran status, or any other characteristic protected under applicable law. Where required, we will provide reasonable accommodation to applicants with known disabilities or chronic illnesses during the

Associate Scientist, Host Cell Protein (HCP) Analytics at Regeneron — TARRYTOWN | Yoinka